Tocilizumab in Graves’ orbitopathy

This prospective European study looks at the response to tocilizumab in corticosteroid-resistant disease. Tocilizumab (TCZ) is a monoclonal antibody that competitively inhibits IL-6 binding to its receptor. Unlike teprotumumab, the advantage of TCZ is that it is already used within...

Recession and resection surgery in TED

The aim was to investigate changes in ocular ductions in thyroid eye disease (TED) patients undergoing recession in comparison to recession / resection surgery. This was a retrospective study of 119 patients with inclusion of 102 eyes in final analysis....

OCT-A imaging in Grave’s orbitopathy and orbital decompression

In this case series of 12 patients and 24 orbits, the authors describe the changes in the optic nerve and peripapillary blood vessel density in patients with moderate to severe Grave’s Orbitopathy (GO) undergoing orbital decompression. The patients undergoing orbital...

Use of bovine pericardium for tendon elongation

A retrospective analysis was conducted on all patients treated in one centre with tendon elongation using bovine pericardium (BP) to examine outcomes and long-term safety. The study included 60 patients; 27 unilateral and 33 bilateral cases. Follow-up of one to...

AlloDerm for correction of lower lid retraction

This is a retrospective review of 95 eyes of 54 patients undergoing orbital decompression for Graves’ orbitopathy. All patients had a swinging eyelid approach across the whole of the lower lid. Thirty-six eyes also had insertion of a 0.3mm thick...